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New Concepts in Cardiovascular Disease

By April 27, 2015Blog

“New Concepts in Cardiovascular Disease”, Mark C. Huston, MD, MS, FACP, FAHA, FASH, FACN, FAARM, Journal of Restorative Medicine; 2013; 2: page 30

“Cardiovascular medicine needs a complete functional and metabolic reevaluation related to diagnosis, prevention, and integrative treatments. We have reached a limit in our ability to treat cardiovascular disease (CVD) appropriately.”

The typical cardiovascular diseases effect the vessels and the heart and include heart attack, stroke, peripheral artery disease, deep vein thrombosis (DVT), pulmonary embolism, congenital heart disease and rheumatic heart disease. “In these states the cardiovascular system is literally “on fire”; our present treatments are not effective at reducing this vascular inflammation.

Blood Vessel Responses to Insult

“The blood vessel has 3 known finite responses to an infinite number of insults.”:

  1. Inflammation: the body’s normal response to remove any injurious stimuli and to initiate healing.
  2. Oxidative Stress: the body’s normal response to any toxin is to detoxify it, but during the steps of this process free radicals are created that when out of balance or too numerous are damaging.
  3. Autoimmunity: vascular immune dysfunction related to T cell and B cell function in fighting against infection or foreign agents in our body.

“In the acute setting, any vascular insult results in a corrective defensive response by the endothelium. The vascular immune dysfunction, oxidative stress or inflammatory responses are usually short-lived, appropriate, and regulated. However, chronic insults result in a chronic exaggerated and dysregulated vascular dysfunction with preclinical then clinical CVD due to maladaption of various systems such as the rennin-angiotensin-aldosterone (RAAS) system, sympathetic nervous system (SNS) and others.” And …”once endothelial dysfunction has developed, a smaller insult occurring at a later stage can result in a heightened response that induces more vascular damage.”

Endothelial Dysfunction

“Endothelial dysfunction has been hypothesized to be the link between post-prandial state and atherosclerosis and vascular disease”

In other words, you are what you eat!

Eating the following things will increase blood sugars, triglycerides, inflammation, oxidative stress and immune dysfunction:

  1. Sodium Chloride: table salt
  2. Refined Carbohydrates: packaged foods
  3. Trans Fats/Hydogenated Fats and Saturated Fats in processed foods and vegetable oils

But, eating these foods can help decrease blood sugars, triglycerides, inflammation, oxidative stress and immune dysfunction:

  1. Low Glycemic Foods: real vegetables and fruits and non-grains.
  2. Monounsaturated and Polyunsaturated Fats: olive oil, coconut oil/milk, avocado.
  3. Antioxidants: again real fruits and vegetables. Natural foods of many colors!

Scientifically Proven Nutraceuticals and Dietary Factors to Decrease Endothelial Dysfunction

  1. Curcurmin (Tumeric)
  2. Cinnamon
  3. Broccoli
  4. Resveratrol (nutritional supplement, red wine, grapes)
  5. Green Tea
  6. Luteolin (celery, green pepper, rosemary, carrots, oregano, oranges, olives)
  7. Quercetin (tea, apples, onion, tomatoes, capers)
  8. Chrysin
  9. Omega 3 Fatty Acids: Fish Oil/EPA & DHA

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