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Nutraceutical Supplements and the Treatment of Dyslipidemia

By May 18, 2015Blog

“The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia”; Mark Houston, MD; The Journal of Clinical Hypertension; Volume 14; No. 2; February 2012.

Nutritional Supplement Effects on Various Mechanisms of Dyslipidemia-Induced Vascular Disease:

Last week I reviewed four nutritional supplements, so now let’s continue:

E. Monounsaturated Fats: MUFA’s such as olives, olive oil, and nuts reduce LDL by 5%–10%, lower triglycerides by 10%–15%, and increase HDL by 5%. They are one of the most potent agents to decrease oxidized LDL, reduce inflammation, improve erectile dysfunction, lower blood pressure, decrease thrombosis, and reduce incidence of CHD.

Recommended dose= 3-4 tablespoons of extra virgin olive oil.

F. Curcumin: is a phenolic compound in tumeric and curry.

In one study of 10 patients who consumed 500mg daily HDL increased by 29% and total cholesterol fell 12%. Dr. Houston states this needs confirmation in larger studies.

G. Pomegranate: is a potent anti-oxidant. It lowers oxLDL, decreases antibodies to oxLDL, inhibits platelet function, reduces glycosylated LDL, decreases macrophage LDL uptake, reduces lipid deposition in the arterial wall, decreases progression of carotid artery wall thickness, and lowers blood pressure.

Recommended dose= 8 oz. daily.

H. Garlic: Reduces intestinal absorption of cholesterol, deactivates HMG-COA reductase, lowers blood pressure, has fibrinolytic activity, anti-platelet activity, reduces oxLDL, and decreases coronary artery calcification by electron beam tomography.

Numerous placebo-controlled trials have shown reductions in total cholesterol and LDL of between 9% and 12%.

Recommended dose= 600mg—900mg of standardized extract of allicin and ajoene.

I. Sesame: A randomized controlled trial with crossover of 26 postmenopausal women who consumed 50 grams of sesame powder daily for 5 weeks had a 5% decrease in total cholesterol and a 10% decrease in LDL. It inhibits intestinal absorption of cholesterol, increases biliary secretion, decreases HMG-COA reductase and upregulates the LDL receptor gene.

Recommended dose= 40 grams daily

Continue to check out my blog each week this month as I continue to review the nutritional supplements that have a positive effect on Dyslipidemia-induced vascular disease.

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